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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRPK1 All Species: 40
Human Site: Y202 Identified Species: 73.33
UniProt: Q96SB4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96SB4 NP_003128.3 655 74325 Y202 Q V L Q G L D Y L H T K C R I
Chimpanzee Pan troglodytes XP_518428 831 92792 Y378 Q V L Q G L D Y L H T K C R I
Rhesus Macaque Macaca mulatta XP_001116721 831 92803 Y378 Q V L Q G L D Y L H T K C R I
Dog Lupus familis XP_850330 823 92006 Y370 Q V L Q G L D Y L H T K C R I
Cat Felis silvestris
Mouse Mus musculus O70551 648 73070 Y202 Q V L Q G L D Y L H T K C R I
Rat Rattus norvegicus NP_001020897 655 73837 Y202 Q V L Q G L D Y L H T K C R I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516210 528 59280 Q145 K K K L K K K Q K R Q A E L L
Chicken Gallus gallus XP_419265 754 84415 Y293 Q V L Q G L D Y L H T K C R I
Frog Xenopus laevis NP_001085122 605 68633 Y202 Q V L Q G L D Y L H S R C Q I
Zebra Danio Brachydanio rerio NP_001074138 640 71523 Y199 Q V L Q G L D Y L H T K C K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q03563 1003 112508 G279 E M R S A K E G E E S E G T I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P51567 427 49548 E44 V G M F C G Q E I G N I S S F
Baker's Yeast Sacchar. cerevisiae Q03656 742 83219 Y283 Q L L L G L D Y M H R R C G I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.5 78.2 76.7 N.A. 91.4 91.4 N.A. 65.5 70.1 67.6 64.7 N.A. N.A. N.A. 23.1 N.A.
Protein Similarity: 100 78.6 78.5 77.6 N.A. 94.6 94 N.A. 70.3 77.3 78.1 76.1 N.A. N.A. N.A. 37.1 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 100 80 93.3 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 100 100 100 N.A. N.A. N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 20.3 32.2 N.A.
Protein Similarity: N.A. N.A. N.A. 36 49.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 60 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 77 0 0 % C
% Asp: 0 0 0 0 0 0 77 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 8 8 8 8 0 8 8 0 0 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 8 0 0 77 8 0 8 0 8 0 0 8 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 77 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 85 % I
% Lys: 8 8 8 0 8 16 8 0 8 0 0 62 0 8 0 % K
% Leu: 0 8 77 16 0 77 0 0 70 0 0 0 0 8 8 % L
% Met: 0 8 8 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 77 0 0 70 0 0 8 8 0 0 8 0 0 8 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 8 8 16 0 54 0 % R
% Ser: 0 0 0 8 0 0 0 0 0 0 16 0 8 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 62 0 0 8 0 % T
% Val: 8 70 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 77 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _